人 EOMES (NM_001278183) cDNA克隆

基本信息

Accession: NM_001278183
基因名称: EOMES
基因别名: TBR2
基因描述: Homo sapiens eomesodermin (EOMES), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1233 (查看编码区序列)
翻译后氨基酸长度: 410 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR, 5' coding region and initiates translation at a downstream AUG, compared to variant 1. It encodes isoform 3 which has a shorter N-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G170440 人 EOMES (NM_001278183) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 EOMES (NM_001278182) cDNA克隆 transcript variant 1
人 EOMES (NM_005442) cDNA克隆 transcript variant 2
人 EOMES (NM_001278183) cDNA克隆 transcript variant 3

基因简介

This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

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