人 EOMES (NM_001278182) cDNA克隆

Accession: NM_001278182
基因名称: EOMES
基因别名: TBR2
基因描述: Homo sapiens eomesodermin (EOMES), transcript variant 1, mRNA.
种属: Human
CDS区长度: 2118 (查看编码区序列)
翻译后氨基酸长度: 705 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
产品编号 产品名称 载体 规格 价格
G170439 人 EOMES (NM_001278182) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]