人 RUNX3 (NM_004350) cDNA克隆

基本信息

Accession: NM_004350
基因名称: RUNX3
基因别名: AML2; CBFA3; PEBP2aC
基因描述: Homo sapiens runt-related transcription factor 3 (RUNX3), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1248 (查看编码区序列)
翻译后氨基酸长度: 415 (查看氨基酸序列)
Transcript Variant: This variant (2), also known as p44, contains a distinct 5' UTR and uses an alternate translation initiation site, compared to variant 1. The resulting isoform (2) has a shorter and distinct N-terminus when compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G166908 人 RUNX3 (NM_004350) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 RUNX3 (NM_001031680) cDNA克隆 transcript variant 1
人 RUNX3 (NM_004350) cDNA克隆 transcript variant 2

基因简介

This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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