人 RUNX1 (NM_001754) cDNA克隆

基本信息

Accession: NM_001754
基因名称: RUNX1
基因别名: AML1; CBFA2; EVI-1; AMLCR1; PEBP2aB; AML1-EVI-1
基因描述: Homo sapiens runt-related transcription factor 1 (RUNX1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1443 (查看编码区序列)
翻译后氨基酸长度: 480 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest isoform (AML1c).

订购信息

产品编号 产品名称 载体 规格 价格
G166896 人 RUNX1 (NM_001754) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 RUNX1 (NM_001754) cDNA克隆 transcript variant 1
人 RUNX1 (NM_001001890) cDNA克隆 transcript variant 2
人 RUNX1 (NM_001122607) cDNA克隆 transcript variant 3

基因简介

Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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