人 PIF1 (NM_001286496) cDNA克隆

基本信息

Accession: NM_001286496
基因名称: PIF1
基因别名: PIF; C15orf20
基因描述: Homo sapiens PIF1 5'-to-3' DNA helicase (PIF1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1926 (查看编码区序列)
翻译后氨基酸长度: 641 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript. This variant can initiate translation from both an upstream and a downstream AUG start codon. The isoform represented in this variant (a, also known as alpha or alpha-1) initiates translation from the upstream AUG. This isoform localizes to the nucleus (PMID: 17827721). Variants 1 and 2 encode the same isoform (a).

订购信息

产品编号 产品名称 载体 规格 价格
G165580 人 PIF1 (NM_001286496) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PIF1 (NM_001286496) cDNA克隆 transcript variant 1
人 PIF1 (NM_001286499) cDNA克隆 transcript variant 1
人 PIF1 (NM_025049) cDNA克隆 transcript variant 2
人 PIF1 (NM_001286497) cDNA克隆 transcript variant 3

基因简介

This gene encodes a DNA-dependent adenosine triphosphate (ATP)-metabolizing enzyme that functions as a 5' to 3' DNA helicase. The encoded protein can resolve G-quadruplex structures and RNA-DNA hybrids at the ends of chromosomes. It also prevents telomere elongation by inhibiting the actions of telomerase. Alternative splicing and the use of alternative start codons results in multiple isoforms that are differentially localized to either the mitochondria or the nucleus. [provided by RefSeq, Nov 2013]

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