人 TCF7 (NM_213648) cDNA克隆

基本信息

Accession: NM_213648
基因名称: TCF7
基因别名: TCF-1
基因描述: Homo sapiens transcription factor 7 (T-cell specific, HMG-box) (TCF7), transcript variant 5, mRNA.
种属: Human
CDS区长度: 810 (查看编码区序列)
翻译后氨基酸长度: 269 (查看氨基酸序列)
Transcript Variant: This variant (5) differs in the 5' UTR, lacks a portion of the 5' coding region, and uses a downstream start codon, compared to variant 1. The resulting isoform (2) is shorter at the N-terminus, compared to isoform 1. Both variants 2 and 5 encode the same isoform.

订购信息

产品编号 产品名称 载体 规格 价格
G161402 人 TCF7 (NM_213648) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 TCF7 (NM_003202) cDNA克隆 transcript variant 1
人 TCF7 (NM_201632) cDNA克隆 transcript variant 2
人 TCF7 (NM_001134851) cDNA克隆 transcript variant 3
人 TCF7 (NM_201633) cDNA克隆 transcript variant 3
人 TCF7 (NM_201634) cDNA克隆 transcript variant 4
人 TCF7 (NM_213648) cDNA克隆 transcript variant 5

基因简介

The protein encoded by this gene is a transcriptional activator that plays an important role in lymphocyte differentiation. This gene is expressed predominantly in T-cells. The encoded protein can bind an enhancer element and activate the CD3E gene, and it also may repress the CTNNB1 and TCF7L2 genes through a feedback mechanism. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

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