人 TCF7 (NM_201633) cDNA克隆

Accession: NM_201633
基因名称: TCF7
基因别名: TCF-1
基因描述: Homo sapiens transcription factor 7 (T-cell specific, HMG-box) (TCF7), transcript variant 3, mRNA.
种属: Human
CDS区长度: 810 (查看编码区序列)
翻译后氨基酸长度: 269 (查看氨基酸序列)
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G161400 人 TCF7 (NM_201633) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a transcriptional activator that plays an important role in lymphocyte differentiation. This gene is expressed predominantly in T-cells. The encoded protein can bind an enhancer element and activate the CD3E gene, and it also may repress the CTNNB1 and TCF7L2 genes through a feedback mechanism. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]