人 WNK3 (NM_001002838) cDNA克隆

Accession: NM_001002838
基因名称: WNK3
基因别名: PRKWNK3
基因描述: Homo sapiens WNK lysine deficient protein kinase 3 (WNK3), transcript variant 2, mRNA.
种属: Human
CDS区长度: 5232 (查看编码区序列)
翻译后氨基酸长度: 1743 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate in-frame splice site in the central coding region and lacks an alternate in-frame exon in the 3' coding region, compared to variant 1, resulting in an isoform (2) that is shorter than isoform 1.
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G158357 人 WNK3 (NM_001002838) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a protein belonging to the 'with no lysine' family of serine-threonine protein kinases. These family members lack the catalytic lysine in subdomain II, and instead have a conserved lysine in subdomain I. This family member functions as a positive regulator of the transcellular Ca2+ transport pathway, and it plays a role in the increase of cell survival in a caspase-3-dependent pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]