人 WNK1 (NM_213655) cDNA克隆

基本信息

Accession: NM_213655
基因名称: WNK1
基因别名: KDP; PSK; p65; HSN2; HSAN2; PRKWNK1
基因描述: Homo sapiens WNK lysine deficient protein kinase 1 (WNK1), transcript variant 3, mRNA.
种属: Human
CDS区长度: 7905 (查看编码区序列)
翻译后氨基酸长度: 2634 (查看氨基酸序列)
Transcript Variant: This variant (3) has multiple differences in the coding region but maintains the reading frame compared to variant 1. This variant represents the exon combination of the brain and spinal cord variant described in Figure 2F of PubMed ID 18521183. This variant encodes isoform 3, which is longer than isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G120898 人 WNK1 (NM_213655) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 WNK1 (NM_018979) cDNA克隆 transcript variant 1
人 WNK1 (NM_014823) cDNA克隆 transcript variant 2
人 WNK1 (NM_213655) cDNA克隆 transcript variant 3
人 WNK1 (NM_001184985) cDNA克隆 transcript variant 4

基因简介

This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions. Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II. Alternatively spliced transcript variants encoding different isoforms have been described but the full-length nature of all of them has yet to be determined.[provided by RefSeq, May 2010]

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