人 ERAP2 (NM_001130140) cDNA克隆

基本信息

Accession: NM_001130140
基因名称: ERAP2
基因别名: LRAP; L-RAP
基因描述: Homo sapiens endoplasmic reticulum aminopeptidase 2 (ERAP2), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2883 (查看编码区序列)
翻译后氨基酸长度: 960 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein.

订购信息

产品编号 产品名称 载体 规格 价格
G157777 人 ERAP2 (NM_001130140) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ERAP2 (NM_022350) cDNA克隆 transcript variant 1
人 ERAP2 (NM_001130140) cDNA克隆 transcript variant 2

基因简介

Aminopeptidases hydrolyze N-terminal amino acids of proteins or peptide substrates. Major histocompatibility complex (MHC) class I molecules rely on aminopeptidases such as ERAP1 (MIM 606832) and LRAP to trim precursors to antigenic peptides in the endoplasmic reticulum (ER) following cleavage in the cytoplasm by tripeptidyl peptidase II (TPP2; MIM 190470) (Tanioka et al., 2003 [PubMed 12799365]).[supplied by OMIM, Mar 2008]

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