人 ERAP1 (NM_001040458) cDNA克隆

基本信息

Accession: NM_001040458
基因名称: ERAP1
基因别名: ALAP; A-LAP; ARTS1; ERAAP; APPILS; ARTS-1; ERAAP1; PILSAP; PILS-AP
基因描述: Homo sapiens endoplasmic reticulum aminopeptidase 1 (ERAP1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2826 (查看编码区序列)
翻译后氨基酸长度: 941 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (b) has a shorter and distinct C-terminus compared to isoform a. Variants 2 and 3 both encode the same isoform.

订购信息

产品编号 产品名称 载体 规格 价格
G154073 人 ERAP1 (NM_001040458) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ERAP1 (NM_016442) cDNA克隆 transcript variant 1
人 ERAP1 (NM_001040458) cDNA克隆 transcript variant 2
人 ERAP1 (NM_001198541) cDNA克隆 transcript variant 3

基因简介

The protein encoded by this gene is an aminopeptidase involved in trimming HLA class I-binding precursors so that they can be presented on MHC class I molecules. The encoded protein acts as a monomer or as a heterodimer with ERAP2. This protein may also be involved in blood pressure regulation by inactivation of angiotensin II. Three transcript variants encoding two different isoforms have been found for this gene.[provided by RefSeq, Oct 2010]

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