人 ROBO2 (NM_001128929) cDNA克隆

Accession: NM_001128929
基因名称: ROBO2
基因别名: SAX3
基因描述: Homo sapiens roundabout, axon guidance receptor, homolog 2 (Drosophila) (ROBO2), transcript variant 1, mRNA.
种属: Human
CDS区长度: 4185 (查看编码区序列)
翻译后氨基酸长度: 1394 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the longer protein (isoform ROBO2a).
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G157239 人 ROBO2 (NM_001128929) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene belongs to the ROBO family, part of the immunoglobulin superfamily proteins that are highly conserved from fly to human. The encoded protein is a receptor for SLIT2, molecules known to function in axon guidance and cell migration. Defects in this gene are the cause of vesicoureteral reflux type 2. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]