人 PTPRN2 (NM_130843) cDNA克隆

基本信息

Accession: NM_130843
基因名称: PTPRN2
基因别名: IAR; ICAAR; PTPRP; IA-2beta; R-PTP-N2
基因描述: Homo sapiens protein tyrosine phosphatase, receptor type, N polypeptide 2 (PTPRN2), transcript variant 3, mRNA.
种属: Human
CDS区长度: 2961 (查看编码区序列)
翻译后氨基酸长度: 986 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an internal fragment within the coding region when compared to variant 1. The translation remains in-frame, and thus results in a protein that lacks a 29 aa internal segment, as compared to isoform (1).

订购信息

产品编号 产品名称 载体 规格 价格
G156736 人 PTPRN2 (NM_130843) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PTPRN2 (NM_002847) cDNA克隆 transcript variant 1
人 PTPRN2 (NM_130842) cDNA克隆 transcript variant 2
人 PTPRN2 (NM_130843) cDNA克隆 transcript variant 3

基因简介

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. The catalytic domain of this PTP is most closely related to PTPRN/IA-2beta. This PTP and PTPRN are both found to be major autoantigens associated with insulin-dependent diabetes mellitus. Three alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008]

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