人 PTPRN (NM_001199764) cDNA克隆

基本信息

Accession: NM_001199764
基因名称: PTPRN
基因别名: IA2; IA-2; ICA512; R-PTP-N; IA-2/PTP
基因描述: Homo sapiens protein tyrosine phosphatase, receptor type, N (PTPRN), transcript variant 3, mRNA.
种属: Human
CDS区长度: 2670 (查看编码区序列)
翻译后氨基酸长度: 889 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR and has multiple coding region differences, compared to variant 1. These differences causes translation initiation at a downstream AUG and results an isoform (3) with a shorter N-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G112397 人 PTPRN (NM_001199764) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PTPRN (NM_002846) cDNA克隆 transcript variant 1
人 PTPRN (NM_001199763) cDNA克隆 transcript variant 2
人 PTPRN (NM_001199764) cDNA克隆 transcript variant 3

基因简介

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010]

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