人 PLEKHG5 (NM_001265594) cDNA克隆

Accession: NM_001265594
基因名称: PLEKHG5
基因别名: Syx; Tech; DSMA4; CMTRIC; GEF720
基因描述: Homo sapiens pleckstrin homology domain containing, family G (with RhoGef domain) member 5 (PLEKHG5), transcript variant 8, mRNA.
种属: Human
CDS区长度: 2793 (查看编码区序列)
翻译后氨基酸长度: 930 (查看氨基酸序列)
Transcript Variant: This variant (8) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at an alternate start codon, and uses an alternate splice site in the 3' coding region which results in a frameshift compared to variant 1. The encoded protein (isoform f) is shorter and has distinct N- and C-termini compared to isoform b.
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G156498 人 PLEKHG5 (NM_001265594) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a protein that activates the nuclear factor kappa B (NFKB1) signaling pathway. Mutations in this gene are associated with autosomal recessive distal spinal muscular atrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]