This gene encodes a protein belonging to the Rho guanine exchange factor (GEF) family of proteins, which activate GTPases by replacing GDP with GTP. This family member is a RhoA GEF that plays a role in endothelial cell migration and tube formation. It is required for angiogenesis and may function in neuronal cell differentiation. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Oct 2013]
小鼠 Plekhg5 (NM_001285999) cDNA克隆
| Accession: | NM_001285999 |
|---|---|
| 基因名称: | Plekhg5 |
| 基因别名: | Syx; BC023181 |
| 基因描述: | Mus musculus pleckstrin homology domain containing, family G (with RhoGef domain) member 5 (Plekhg5), transcript variant 1, mRNA. |
| 种属: | Mouse |
| CDS区长度: | 3222 (查看编码区序列) |
| 翻译后氨基酸长度: | 1073 (查看氨基酸序列) |
| Transcript Variant: | This variant (1, also known as Syx1) represents the longer transcript and encodes the supported protein. |
| 小鼠 Plekhg5 (NM_001285999) cDNA克隆 | transcript variant 1 |
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