人 PTGS1 (NM_001271367) cDNA克隆

基本信息

Accession: NM_001271367
基因名称: PTGS1
基因别名: COX1; COX3; PHS1; PCOX1; PES-1; PGHS1; PTGHS; PGG/HS; PGHS-1
基因描述: Homo sapiens prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) (PTGS1), transcript variant 6, mRNA.
种属: Human
CDS区长度: 1362 (查看编码区序列)
翻译后氨基酸长度: 453 (查看氨基酸序列)
Transcript Variant: This variant (6) uses two alternate splice sites at internal exons, compared to variant 1. These differences result in initiation of translation at an alternate downstream in-frame start site, compared to variant 1. The primary ORF can be translated due to a combination of reinitiation and leaky scanning. The encoded isoform (5) is shorter than isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G156453 人 PTGS1 (NM_001271367) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PTGS1 (NM_000962) cDNA克隆 transcript variant 1
人 PTGS1 (NM_080591) cDNA克隆 transcript variant 2
人 PTGS1 (NM_001271164) cDNA克隆 transcript variant 3
人 PTGS1 (NM_001271165) cDNA克隆 transcript variant 4
人 PTGS1 (NM_001271166) cDNA克隆 transcript variant 5
人 PTGS1 (NM_001271367) cDNA克隆 transcript variant 6
人 PTGS1 (NM_001271368) cDNA克隆 transcript variant 7

基因简介

This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012]

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