人 PTGS1 (NM_080591) cDNA克隆

Accession: NM_080591
基因名称: PTGS1
基因别名: COX1; COX3; PHS1; PCOX1; PES-1; PGHS1; PTGHS; PGG/HS; PGHS-1
基因描述: Homo sapiens prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) (PTGS1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1689 (查看编码区序列)
翻译后氨基酸长度: 562 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate in-frame splice site in the coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
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G156449 人 PTGS1 (NM_080591) cDNA克隆 pDONR223 2ug质粒 点击询价

This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012]