人 PRLR (NM_001204314) cDNA克隆

基本信息

Accession: NM_001204314
基因名称: PRLR
基因别名: HPRL; MFAB; hPRLrI
基因描述: Homo sapiens prolactin receptor (PRLR), transcript variant 6, mRNA.
种属: Human
CDS区长度: 1566 (查看编码区序列)
翻译后氨基酸长度: 521 (查看氨基酸序列)
Transcript Variant: This variant (6) lacks two in-frame coding exons compared to variant 1. This results in a shorter isoform (6, also known as deltaS1) missing an internal protein segment coding for the S1 motif, compared to isoform 1. This isoform has been shown to be expressed at the protein level on the cell surface, and is functional (PMID:12351696).

订购信息

产品编号 产品名称 载体 规格 价格
G155676 人 PRLR (NM_001204314) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PRLR (NM_000949) cDNA克隆 transcript variant 1
人 PRLR (NM_001204315) cDNA克隆 transcript variant 2
人 PRLR (NM_001204316) cDNA克隆 transcript variant 3
人 PRLR (NM_001204317) cDNA克隆 transcript variant 4
人 PRLR (NM_001204318) cDNA克隆 transcript variant 5
人 PRLR (NM_001204314) cDNA克隆 transcript variant 6

基因简介

This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq, Feb 2011]

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