人 TREM2 (NM_001271821) cDNA克隆

基本信息

Accession: NM_001271821
基因名称: TREM2
基因别名: TREM-2; Trem2a; Trem2b; Trem2c
基因描述: Homo sapiens triggering receptor expressed on myeloid cells 2 (TREM2), transcript variant 2, mRNA.
种属: Human
CDS区长度: 660 (查看编码区序列)
翻译后氨基酸长度: 219 (查看氨基酸序列)
Transcript Variant: This variant (2), alternately referred to as TREM-2V, lacks a 3' coding exon which results in a frameshift, compared to variant 1. The resulting isoform (2) is shorter compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G154676 人 TREM2 (NM_001271821) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 TREM2 (NM_018965) cDNA克隆 transcript variant 1
人 TREM2 (NM_001271821) cDNA克隆 transcript variant 2

基因简介

This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012]

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