人 TREM1 (NM_001242589) cDNA克隆

基本信息

Accession: NM_001242589
基因名称: TREM1
基因别名: CD354; TREM-1
基因描述: Homo sapiens triggering receptor expressed on myeloid cells 1 (TREM1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 678 (查看编码区序列)
翻译后氨基酸长度: 225 (查看氨基酸序列)
Transcript Variant: This variant (2) differs at the 3' end compared to variant 1. This results in a shorter isoform (2) with a distinct C-terminus, lacking the transmembrane domain, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G118807 人 TREM1 (NM_001242589) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 TREM1 (NM_018643) cDNA克隆 transcript variant 1
人 TREM1 (NM_001242589) cDNA克隆 transcript variant 2
人 TREM1 (NM_001242590) cDNA克隆 transcript variant 3

基因简介

This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011]

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