人 PDE4A (NM_001111307) cDNA克隆

Accession: NM_001111307
基因名称: PDE4A
基因别名: PDE4; DPDE2; PDE46
基因描述: Homo sapiens phosphodiesterase 4A, cAMP-specific (PDE4A), transcript variant 1, mRNA.
种属: Human
CDS区长度: 2661 (查看编码区序列)
翻译后氨基酸长度: 886 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the longest isoform (1).
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G153958 人 PDE4A (NM_001111307) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]