人 NFATC2 (NM_001258296) cDNA克隆

基本信息

Accession: NM_001258296
基因名称: NFATC2
基因别名: NFAT1; NFATP
基因描述: Homo sapiens nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 (NFATC2), transcript variant 7, mRNA.
种属: Human
CDS区长度: 2109 (查看编码区序列)
翻译后氨基酸长度: 702 (查看氨基酸序列)
Transcript Variant: This variant (7) uses an alternate splice junction at the 5' end of a coding exon and contains an alternate exon in the 3' end compared to variant 2, that causes a frameshift. The resulting isoform (F) is shorter at the N-terminus and has a shorter and distinct C-terminus compared to isoform C. Variants 5 and 7 both encode the same isoform (F).

订购信息

产品编号 产品名称 载体 规格 价格
G152940 人 NFATC2 (NM_001258296) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 NFATC2 (NM_012340) cDNA克隆 transcript variant 1
人 NFATC2 (NM_173091) cDNA克隆 transcript variant 2
人 NFATC2 (NM_001136021) cDNA克隆 transcript variant 3
人 NFATC2 (NM_001258292) cDNA克隆 transcript variant 4
人 NFATC2 (NM_001258294) cDNA克隆 transcript variant 5
人 NFATC2 (NM_001258295) cDNA克隆 transcript variant 6
人 NFATC2 (NM_001258296) cDNA克隆 transcript variant 7
人 NFATC2 (NM_001258297) cDNA克隆 transcript variant 8

基因简介

This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Apr 2012]

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