人 NFATC2 (NM_173091) cDNA克隆

Accession: NM_173091
基因名称: NFATC2
基因别名: NFAT1; NFATP
基因描述: Homo sapiens nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 (NFATC2), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2778 (查看编码区序列)
翻译后氨基酸长度: 925 (查看氨基酸序列)
Transcript Variant: This variant (2) encodes the longest isoform (C).
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G152935 人 NFATC2 (NM_173091) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Apr 2012]