人 INSC (NM_001278316) cDNA克隆

Accession: NM_001278316
基因名称: INSC
基因描述: Homo sapiens inscuteable homolog (Drosophila) (INSC), transcript variant 6, mRNA.
种属: Human
CDS区长度: 1473 (查看编码区序列)
翻译后氨基酸长度: 490 (查看氨基酸序列)
Transcript Variant: This variant (6) differs in the 5' UTR and has multiple coding region differences, compared to variant 1. The resulting isoform (e) is shorter at the N-terminus and lacks an internal segment, compared to isoform a.
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G151559 人 INSC (NM_001278316) cDNA克隆 pDONR223 2ug质粒 点击询价

In Drosophila, neuroblasts divide asymmetrically into another neuroblast at the apical side and a smaller ganglion mother cell on the basal side. Cell polarization is precisely regulated by 2 apically localized multiprotein signaling complexes that are tethered by Inscuteable, which regulates their apical localization (Izaki et al., 2006 [PubMed 16458856]).[supplied by OMIM, Mar 2008]