人 INSC (NM_001278313) cDNA克隆

基本信息

Accession: NM_001278313
基因名称: INSC
基因描述: Homo sapiens inscuteable homolog (Drosophila) (INSC), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1599 (查看编码区序列)
翻译后氨基酸长度: 532 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an exon at the 5' end but has an alternate segment, which results in a downstream start codon, compared to variant 1. The resulting isoform (b) has a shorter N-terminus, compared to isoform a. Variants 2 and 3 encode the same isoform b.

订购信息

产品编号 产品名称 载体 规格 价格
G151556 人 INSC (NM_001278313) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 INSC (NM_001031853) cDNA克隆 transcript variant 1
人 INSC (NM_001042536) cDNA克隆 transcript variant 2
人 INSC (NM_001278313) cDNA克隆 transcript variant 3
人 INSC (NM_001278314) cDNA克隆 transcript variant 4
人 INSC (NM_001278315) cDNA克隆 transcript variant 5
人 INSC (NM_001278316) cDNA克隆 transcript variant 6

基因简介

In Drosophila, neuroblasts divide asymmetrically into another neuroblast at the apical side and a smaller ganglion mother cell on the basal side. Cell polarization is precisely regulated by 2 apically localized multiprotein signaling complexes that are tethered by Inscuteable, which regulates their apical localization (Izaki et al., 2006 [PubMed 16458856]).[supplied by OMIM, Mar 2008]

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