人 ING1 (NM_001267728) cDNA克隆

基本信息

Accession: NM_001267728
基因名称: ING1
基因别名: p33; p47; p33ING1; p24ING1c; p33ING1b; p47ING1a
基因描述: Homo sapiens inhibitor of growth family, member 1 (ING1), transcript variant 5, mRNA.
种属: Human
CDS区长度: 789 (查看编码区序列)
翻译后氨基酸长度: 262 (查看氨基酸序列)
Transcript Variant: This variant (5) lacks an internal segment in the 5' coding region, compared to variant 4. The resulting isoform (E) lacks an internal segment, as compared to isoform D.

订购信息

产品编号 产品名称 载体 规格 价格
G150412 人 ING1 (NM_001267728) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ING1 (NM_198219) cDNA克隆 transcript variant 1
人 ING1 (NM_198218) cDNA克隆 transcript variant 2
人 ING1 (NM_198217) cDNA克隆 transcript variant 3
人 ING1 (NM_005537) cDNA克隆 transcript variant 4
人 ING1 (NM_001267728) cDNA克隆 transcript variant 5

基因简介

This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

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