人 ING4 (NM_001127586) cDNA克隆

Accession: NM_001127586
基因名称: ING4
基因别名: my036; p29ING4
基因描述: Homo sapiens inhibitor of growth family, member 4 (ING4), transcript variant 6, mRNA.
种属: Human
CDS区长度: 540 (查看编码区序列)
翻译后氨基酸长度: 179 (查看氨基酸序列)
Transcript Variant: This variant (6) lacks an alternate segment in the 3' coding region. which changes the reading frame, compared to variant 9. The resulting protein (isoform 6) is shorter and has a distinct C-terminus when it is compared to isoform 9. Another name for this variant is delta Ex6A.
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G103645 人 ING4 (NM_001127586) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a tumor suppressor protein that contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in the TP53-dependent regulatory pathway. Multiple alternatively spliced transcript variants have been observed that encode distinct proteins. [provided by RefSeq, Jul 2008]