人 GPX5 (NM_003996) cDNA克隆

Accession: NM_003996
基因名称: GPX5
基因描述: Homo sapiens glutathione peroxidase 5 (epididymal androgen-related protein) (GPX5), transcript variant 2, mRNA.
种属: Human
CDS区长度: 303 (查看编码区序列)
翻译后氨基酸长度: 100 (查看氨基酸序列)
Transcript Variant: This variant (2) is missing an internal coding exon compared to transcript variant 1. This results in a frame-shift and a shorter isoform (2) with a distinct C-terminus compared to isoform 1.
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G145887 人 GPX5 (NM_003996) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene belongs to the glutathione peroxidase family. It is specifically expressed in the epididymis in the mammalian male reproductive tract, and is androgen-regulated. Unlike mRNAs for other characterized glutathione peroxidases, this mRNA does not contain a selenocysteine (UGA) codon. Thus, the encoded protein is selenium-independent, and has been proposed to play a role in protecting the membranes of spermatozoa from the damaging effects of lipid peroxidation and/or preventing premature acrosome reaction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2008]