人 BACE2 (NM_138992) cDNA克隆

基本信息

Accession: NM_138992
基因名称: BACE2
基因别名: ASP1; BAE2; DRAP; AEPLC; ALP56; ASP21; CDA13; CEAP1
基因描述: Homo sapiens beta-site APP-cleaving enzyme 2 (BACE2), transcript variant b, mRNA.
种属: Human
CDS区长度: 1191 (查看编码区序列)
翻译后氨基酸长度: 396 (查看氨基酸序列)
Transcript Variant: This variant (b) lacks an exon in the 3' coding region, which results in a frameshift, compared to variant a. The encoded isoform (B) is shorter and has a distinct C-terminus, compared to isoform A.

订购信息

产品编号 产品名称 载体 规格 价格
G143251 人 BACE2 (NM_138992) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 BACE2 (NM_012105) cDNA克隆 transcript variant a
人 BACE2 (NM_138992) cDNA克隆 transcript variant b
人 BACE2 (NM_138991) cDNA克隆 transcript variant c

基因简介

This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

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