人 BACE1 (NM_012104) cDNA克隆

基本信息

Accession: NM_012104
基因名称: BACE1
基因别名: ASP2; BACE; HSPC104
基因描述: Homo sapiens beta-site APP-cleaving enzyme 1 (BACE1), transcript variant a, mRNA.
种属: Human
CDS区长度: 1506 (查看编码区序列)
翻译后氨基酸长度: 501 (查看氨基酸序列)
Transcript Variant: This variant (a) is the longest transcript and it encodes the longest isoform (A).

订购信息

产品编号 产品名称 载体 规格 价格
G119349 人 BACE1 (NM_012104) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 BACE1 (NM_012104) cDNA克隆 transcript variant a
人 BACE1 (NM_138972) cDNA克隆 transcript variant b
人 BACE1 (NM_138971) cDNA克隆 transcript variant c
人 BACE1 (NM_138973) cDNA克隆 transcript variant d
人 BACE1 (NM_001207048) cDNA克隆 transcript variant e
人 BACE1 (NM_001207049) cDNA克隆 transcript variant f

基因简介

Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011]

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