人 IQSEC2 (NM_001243197) cDNA克隆

基本信息

Accession: NM_001243197
基因名称: IQSEC2
基因别名: MRX1; BRAG1
基因描述: Homo sapiens IQ motif and Sec7 domain 2 (IQSEC2), transcript variant 3, mRNA.
种属: Human
CDS区长度: 222 (查看编码区序列)
翻译后氨基酸长度: 73 (查看氨基酸序列)
Transcript Variant: This variant (3) shares no exons with variant 1, and differs in the 3' UTR and coding region compared to variant 2. The encoded isoform (3) is significantly shorter and has a distinct C-terminus, compared to isoform 2.

订购信息

产品编号 产品名称 载体 规格 价格
G140078 人 IQSEC2 (NM_001243197) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 IQSEC2 (NM_001111125) cDNA克隆 transcript variant 1
人 IQSEC2 (NM_015075) cDNA克隆 transcript variant 2
人 IQSEC2 (NM_001243197) cDNA克隆 transcript variant 3

基因简介

This gene encodes a guanine nucleotide exchange factor for the ARF family of small GTP-binding proteins. The encoded protein is a component of the postsynaptic density at excitatory synapses, and may play a critical role in cytoskeletal and synaptic organization through the activation of selected ARF substrates including ARF1 and ARF6. Mutations in this gene have been implicated in nonsyndromic X-linked mental retardation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]

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