人 IQSEC2 (NM_015075) cDNA克隆

基本信息

Accession: NM_015075
基因名称: IQSEC2
基因别名: MRX1; BRAG1
基因描述: Homo sapiens IQ motif and Sec7 domain 2 (IQSEC2), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2850 (查看编码区序列)
翻译后氨基酸长度: 949 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR and has multiple coding region differences, compared to variant 1. These differences cause translation initiation at a novel ATG and an isoform (2) with distinct N- and C-termini, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G140077 人 IQSEC2 (NM_015075) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 IQSEC2 (NM_001111125) cDNA克隆 transcript variant 1
人 IQSEC2 (NM_015075) cDNA克隆 transcript variant 2
人 IQSEC2 (NM_001243197) cDNA克隆 transcript variant 3

基因简介

This gene encodes a guanine nucleotide exchange factor for the ARF family of small GTP-binding proteins. The encoded protein is a component of the postsynaptic density at excitatory synapses, and may play a critical role in cytoskeletal and synaptic organization through the activation of selected ARF substrates including ARF1 and ARF6. Mutations in this gene have been implicated in nonsyndromic X-linked mental retardation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]

相关产品