人 KDM4C (NM_001146696) cDNA克隆

基本信息

Accession: NM_001146696
基因名称: KDM4C
基因别名: GASC1; JHDM3C; JMJD2C; TDRD14C; bA146B14.1
基因描述: Homo sapiens lysine (K)-specific demethylase 4C (KDM4C), transcript variant 4, mRNA.
种属: Human
CDS区长度: 2508 (查看编码区序列)
翻译后氨基酸长度: 835 (查看氨基酸序列)
Transcript Variant: This variant (4) differs in the 5' UTR, 3' UTR, and coding region compared to variant 1, resulting in a protein (isoform 4) that maintains the reading frame but is shorter at both the N- and C-termini, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G140034 人 KDM4C (NM_001146696) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 KDM4C (NM_015061) cDNA克隆 transcript variant 1
人 KDM4C (NM_001146694) cDNA克隆 transcript variant 2
人 KDM4C (NM_001146695) cDNA克隆 transcript variant 3
人 KDM4C (NM_001146696) cDNA克隆 transcript variant 4

基因简介

This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]

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