人 KDM4C (NM_015061) cDNA克隆

Accession: NM_015061
基因名称: KDM4C
基因别名: GASC1; JHDM3C; JMJD2C; TDRD14C; bA146B14.1
基因描述: Homo sapiens lysine (K)-specific demethylase 4C (KDM4C), transcript variant 1, mRNA.
种属: Human
CDS区长度: 3171 (查看编码区序列)
翻译后氨基酸长度: 1056 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
产品编号 产品名称 载体 规格 价格
G140033 人 KDM4C (NM_015061) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]