小鼠 Sgk1 (NM_001161848) cDNA克隆

基本信息

Accession: NM_001161848
基因名称: Sgk1
基因别名: Sgk
基因描述: Mus musculus serum/glucocorticoid regulated kinase 1 (Sgk1), transcript variant 3, mRNA.
种属: Mouse
CDS区长度: 1215 (查看编码区序列)
翻译后氨基酸长度: 404 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR and 5' coding sequence compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a. Both variants 2 and 3 encode the same isoform (b).

订购信息

产品编号 产品名称 载体 规格 价格
G136214 小鼠 Sgk1 (NM_001161848) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

小鼠 Sgk1 (NM_001161845) cDNA克隆 transcript variant 1
小鼠 Sgk1 (NM_001161847) cDNA克隆 transcript variant 2
小鼠 Sgk1 (NM_001161848) cDNA克隆 transcript variant 3
小鼠 Sgk1 (NM_001161849) cDNA克隆 transcript variant 4
小鼠 Sgk1 (NM_001161850) cDNA克隆 transcript variant 5
小鼠 Sgk1 (NM_011361) cDNA克隆 transcript variant 6

基因简介

This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. This enzyme is activated by protein phosphorylation and degraded via the ubiquitination and proteasome pathway. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene was identified on chromosome 12. [provided by RefSeq, Sep 2009]

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