人 ADARB1 (NM_015834) cDNA克隆

Accession: NM_015834
基因名称: ADARB1
基因别名: RED1; ADAR2; DRABA2; DRADA2
基因描述: Homo sapiens adenosine deaminase, RNA-specific, B1 (ADARB1), transcript variant 3, mRNA.
种属: Human
CDS区长度: 2145 (查看编码区序列)
翻译后氨基酸长度: 714 (查看氨基酸序列)
Transcript Variant: This variant (3), also known as DRADA2c, lacks an alternate segment in the 3' coding region, compared to variant 2. The resulting isoform (3) has a shorter and distinct C-terminus, compared to isoform 2, and contains the ALU cassette insert and the short C-terminal region.
产品编号 产品名称 载体 规格 价格
G126741 人 ADARB1 (NM_015834) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region. [provided by RefSeq, Jul 2008]