人 ADARB1 (NM_001160230) cDNA克隆

基本信息

Accession: NM_001160230
基因名称: ADARB1
基因别名: RED1; ADAR2; DRABA2; DRADA2
基因描述: Homo sapiens adenosine deaminase, RNA-specific, B1 (ADARB1), transcript variant 7, mRNA.
种属: Human
CDS区长度: 2025 (查看编码区序列)
翻译后氨基酸长度: 674 (查看氨基酸序列)
Transcript Variant: This variant (7), also known as ADAR2d, lacks the ALU cassette insert and an alternate segment in the 3' coding region, compared to variant 2. The resulting isoform (7) lacks an internal segment and has a shorter and distinct C-terminus, compared to isoform 2, and contains the short C-terminal region.

订购信息

产品编号 产品名称 载体 规格 价格
G126740 人 ADARB1 (NM_001160230) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ADARB1 (NM_001112) cDNA克隆 transcript variant 1
人 ADARB1 (NM_015833) cDNA克隆 transcript variant 2
人 ADARB1 (NM_015834) cDNA克隆 transcript variant 3
人 ADARB1 (NM_001160230) cDNA克隆 transcript variant 7

基因简介

This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region. [provided by RefSeq, Jul 2008]

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