人 KIF13A (NM_001105568) cDNA克隆

Accession: NM_001105568
基因名称: KIF13A
基因别名: RBKIN; bA500C11.2
基因描述: Homo sapiens kinesin family member 13A (KIF13A), transcript variant 4, mRNA.
种属: Human
CDS区长度: 5250 (查看编码区序列)
翻译后氨基酸长度: 1749 (查看氨基酸序列)
Transcript Variant: This variant (4) lacks an alternate in-frame exon in both the central and 3' coding regions, and also includes alternate 3' exon structure and thus differs in the 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (d, also known as KINESIN-13A2) has a distinct C-terminus and is shorter than isoform a.
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G124838 人 KIF13A (NM_001105568) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the kinesin family of microtubule-based motor proteins that function in the positioning of endosomes. This family member can direct mannose-6-phosphate receptor-containing vesicles from the trans-Golgi network to the plasma membrane, and it is necessary for the steady-state distribution of late endosomes/lysosomes. It is also required for the translocation of FYVE-CENT and TTC19 from the centrosome to the midbody during cytokinesis, and it plays a role in melanosome maturation. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]