人 KIF13A (NM_001105567) cDNA克隆

Accession: NM_001105567
基因名称: KIF13A
基因别名: RBKIN; bA500C11.2
基因描述: Homo sapiens kinesin family member 13A (KIF13A), transcript variant 3, mRNA.
种属: Human
CDS区长度: 5274 (查看编码区序列)
翻译后氨基酸长度: 1757 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an alternate in-frame exon in both the central and 3' coding regions, compared to variant 1, resulting in an isoform (c, also known as KINESIN-13A1) that is shorter than isoform a.
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G124837 人 KIF13A (NM_001105567) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the kinesin family of microtubule-based motor proteins that function in the positioning of endosomes. This family member can direct mannose-6-phosphate receptor-containing vesicles from the trans-Golgi network to the plasma membrane, and it is necessary for the steady-state distribution of late endosomes/lysosomes. It is also required for the translocation of FYVE-CENT and TTC19 from the centrosome to the midbody during cytokinesis, and it plays a role in melanosome maturation. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]