人 TLR10 (NM_001195108) cDNA克隆

基本信息

Accession: NM_001195108
基因名称: TLR10
基因别名: CD290
基因描述: Homo sapiens toll-like receptor 10 (TLR10), transcript variant 5, mRNA.
种属: Human
CDS区长度: 2394 (查看编码区序列)
翻译后氨基酸长度: 797 (查看氨基酸序列)
Transcript Variant: This variant (5) lacks an alternate exon in the 5' UTR and uses a different splice site which results in part of the 5' coding region being absent, compared to variant 1. The resulting predicted protein (isoform b) has a shorter N-terminus and is missing a potential signal peptide when it is compared to isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G124465 人 TLR10 (NM_001195108) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 TLR10 (NM_030956) cDNA克隆 transcript variant 1
人 TLR10 (NM_001017388) cDNA克隆 transcript variant 2
人 TLR10 (NM_001195106) cDNA克隆 transcript variant 3
人 TLR10 (NM_001195107) cDNA克隆 transcript variant 4
人 TLR10 (NM_001195108) cDNA克隆 transcript variant 5

基因简介

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is most highly expressed in lymphoid tissues such as spleen, lymph node, thymus, and tonsil. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2010]

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