人 DAOA (NM_001161814) cDNA克隆

基本信息

Accession: NM_001161814
基因名称: DAOA
基因别名: LG72; SG72
基因描述: Homo sapiens D-amino acid oxidase activator (DAOA), transcript variant 3, mRNA.
种属: Human
CDS区长度: 249 (查看编码区序列)
翻译后氨基酸长度: 82 (查看氨基酸序列)
Transcript Variant: This variant (3) has an alternate 5' exon and an additional segment in the 5' coding region, as compared to variant 1, which results in a downstream AUG start codon. The resulting isoform (3) is shorter and has a different N-terminus, as compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G123913 人 DAOA (NM_001161814) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 DAOA (NM_172370) cDNA克隆 transcript variant 1
人 DAOA (NM_001161812) cDNA克隆 transcript variant 2
人 DAOA (NM_001161814) cDNA克隆 transcript variant 3

基因简介

This gene encodes a protein that may function as an activator of D-amino acid oxidase, which degrades the gliotransmitter D-serine, a potent activator of N-methyl-D-aspartate (NMDA) type glutamate receptors. Studies also suggest that one encoded isoform may play a role in mitochondrial function and dendritic arborization. Polymorphisms in this gene have been implicated in susceptibility to schizophrenia and bipolar affective disorder. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Mar 2011]

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