人 DAOA (NM_001161812) cDNA克隆

Accession: NM_001161812
基因名称: DAOA
基因别名: LG72; SG72
基因描述: Homo sapiens D-amino acid oxidase activator (DAOA), transcript variant 2, mRNA.
种属: Human
CDS区长度: 378 (查看编码区序列)
翻译后氨基酸长度: 125 (查看氨基酸序列)
Transcript Variant: This variant (2) has additional segments in the 5' and 3' coding regions, as compared to variant 1, which results in a downstream AUG start codon. The resulting isoform (2) is shorter and has a different N-terminus, as compared to isoform 1.
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G123912 人 DAOA (NM_001161812) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a protein that may function as an activator of D-amino acid oxidase, which degrades the gliotransmitter D-serine, a potent activator of N-methyl-D-aspartate (NMDA) type glutamate receptors. Studies also suggest that one encoded isoform may play a role in mitochondrial function and dendritic arborization. Polymorphisms in this gene have been implicated in susceptibility to schizophrenia and bipolar affective disorder. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Mar 2011]