人 TGFBR3 (NM_001195683) cDNA克隆

基本信息

Accession: NM_001195683
基因名称: TGFBR3
基因别名: BGCAN; betaglycan
基因描述: Homo sapiens transforming growth factor, beta receptor III (TGFBR3), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2553 (查看编码区序列)
翻译后氨基酸长度: 850 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate in-frame splice site in the middle portion of the coding region, compared to variant 1. This results in a shorter protein (isoform b), compared to isoform a. Both variants 2 and 3 encode the same isoform (b).

订购信息

产品编号 产品名称 载体 规格 价格
G122695 人 TGFBR3 (NM_001195683) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 TGFBR3 (NM_003243) cDNA克隆 transcript variant 1
人 TGFBR3 (NM_001195683) cDNA克隆 transcript variant 2
人 TGFBR3 (NM_001195684) cDNA克隆 transcript variant 3

基因简介

This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq, Sep 2010]

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