人 TGFBR1 (NM_004612) cDNA克隆

基本信息

Accession: NM_004612
基因名称: TGFBR1
基因别名: AAT5; ALK5; MSSE; SKR4; ALK-5; LDS1A; LDS2A; TGFR-1; ACVRLK4
基因描述: Homo sapiens transforming growth factor, beta receptor 1 (TGFBR1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1512 (查看编码区序列)
翻译后氨基酸长度: 503 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the longer isoform (1).

订购信息

产品编号 产品名称 载体 规格 价格
G161916 人 TGFBR1 (NM_004612) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 TGFBR1 (NM_004612) cDNA克隆 transcript variant 1
人 TGFBR1 (NM_001130916) cDNA克隆 transcript variant 2

基因简介

The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

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