人 PTPN3 (NM_001145372) cDNA克隆

基本信息

Accession: NM_001145372
基因名称: PTPN3
基因别名: PTPH1; PTP-H1
基因描述: Homo sapiens protein tyrosine phosphatase, non-receptor type 3 (PTPN3), transcript variant 6, mRNA.
种属: Human
CDS区长度: 1746 (查看编码区序列)
翻译后氨基酸长度: 581 (查看氨基酸序列)
Transcript Variant: This variant (6) differs in the 5' UTR, and is missing an in-frame coding exon compared to transcript variant 1, resulting in an isoform (6) with a shorter N-terminus and lacking an internal protein segment compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G122658 人 PTPN3 (NM_001145372) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PTPN3 (NM_002829) cDNA克隆 transcript variant 1
人 PTPN3 (NM_001145368) cDNA克隆 transcript variant 2
人 PTPN3 (NM_001145369) cDNA克隆 transcript variant 3
人 PTPN3 (NM_001145370) cDNA克隆 transcript variant 4
人 PTPN3 (NM_001145371) cDNA克隆 transcript variant 5
人 PTPN3 (NM_001145372) cDNA克隆 transcript variant 6

基因简介

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. P97, a cell cycle regulator involved in a variety of membrane related functions, has been shown to be a substrate of this PTP. This PTP was also found to interact with, and be regulated by adaptor protein 14-3-3 beta. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]

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