人 VCAM1 (NM_001199834) cDNA克隆

Accession: NM_001199834
基因名称: VCAM1
基因别名: CD106; INCAM-100
基因描述: Homo sapiens vascular cell adhesion molecule 1 (VCAM1), transcript variant 3, mRNA.
种属: Human
CDS区长度: 2034 (查看编码区序列)
翻译后氨基酸长度: 677 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an in-frame segment in the CDS compared to transcript variant 1. The resulting isoform (c) lacks an internal segment compared to isoform a.
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G121154 人 VCAM1 (NM_001199834) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2010]