人 VCAM1 (NM_080682) cDNA克隆

Accession: NM_080682
基因名称: VCAM1
基因别名: CD106; INCAM-100
基因描述: Homo sapiens vascular cell adhesion molecule 1 (VCAM1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1944 (查看编码区序列)
翻译后氨基酸长度: 647 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an in-frame exon in the CDS compared to transcript variant 1. The resulting isoform (b) lacks an internal segment compared to isoform a.
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G121153 人 VCAM1 (NM_080682) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2010]