人 PAX3 (NM_001127366) cDNA克隆

基本信息

Accession: NM_001127366
基因名称: PAX3
基因别名: WS1; WS3; CDHS; HUP2
基因描述: Homo sapiens paired box 3 (PAX3), transcript variant PAX3I, mRNA.
种属: Human
CDS区长度: 1452 (查看编码区序列)
翻译后氨基酸长度: 483 (查看氨基酸序列)
Transcript Variant: This variant (PAX3I) differs in the 3' UTR, uses an alternate in-frame splice site in the 5' coding region, and contains an alternate splice pattern in the 3' coding region, compared to variant PAX3. The resulting protein (isoform PAX3i, also known as isoform PAX3dQ-) is longer and has a distinct C-terminus, compared to isoform PAX3.

订购信息

产品编号 产品名称 载体 规格 价格
G120014 人 PAX3 (NM_001127366) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PAX3 (NM_181457) cDNA克隆 transcript variant PAX3
人 PAX3 (NM_000438) cDNA克隆 transcript variant PAX3A
人 PAX3 (NM_013942) cDNA克隆 transcript variant PAX3B
人 PAX3 (NM_181458) cDNA克隆 transcript variant PAX3D
人 PAX3 (NM_181459) cDNA克隆 transcript variant PAX3E
人 PAX3 (NM_181461) cDNA克隆 transcript variant PAX3G
人 PAX3 (NM_181460) cDNA克隆 transcript variant PAX3H
人 PAX3 (NM_001127366) cDNA克隆 transcript variant PAX3I

基因简介

This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini. [provided by RefSeq, Jul 2008]

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