人 PAX8 (NM_013953) cDNA克隆

基本信息

Accession: NM_013953
基因名称: PAX8
基因描述: Homo sapiens paired box 8 (PAX8), transcript variant PAX8D, mRNA.
种属: Human
CDS区长度: 966 (查看编码区序列)
翻译后氨基酸长度: 321 (查看氨基酸序列)
Transcript Variant: This variant (PAX8D) lacks two alternate exons, compared to variant PAX8A, that results in a frameshift and an early stop codon. The encoded isoform (PAX8D) is shorter and has a distinct C-terminus compared to isoform PAX8A.

订购信息

产品编号 产品名称 载体 规格 价格
G106739 人 PAX8 (NM_013953) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PAX8 (NM_003466) cDNA克隆 transcript variant PAX8A
人 PAX8 (NM_013952) cDNA克隆 transcript variant PAX8C
人 PAX8 (NM_013953) cDNA克隆 transcript variant PAX8D
人 PAX8 (NM_013992) cDNA克隆 transcript variant PAX8E

基因简介

This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2010]

相关产品